In order to achieve successful and promising results of the oligonucleotide synthesis some nuances of selecting an Oligo Analyzer tool should be considered. Regardless of the use, whether for diagnostics, therapeutics or research , oligonucleotides need to undergo the scientific process of analysis in an effort to determine quality and functionality. The continuous improvement of both DNA oligo synthesis and RNA oligo synthesis has created a dire need to develop appropriate analyzers. But where does one begin when the world is full of tools that can help to do the seemingly impossible? In this guide you will learn about a particular piece of equipment called oligo analyzers and how to select the right one.

1. Accuracy in Sequence Analysis

The most basic use of any Oligo Analyzer is to confirm the sequence of synthesized oligonucleotides. Precision is important and is paramount in projects that involve the difficult oligonucleotide drug development. Sequencing mistakes can threaten your research or even therapeutic accomplishment.

The present analyzers’ gems include basic algorithms that can detect mismatches, secondary structures, and melting temperatures. These algorithms are used especially in custom oligonucleotide synthesis, where the particular sequence can be approached by just one kind of reagent and has to be thoroughly tested. For developers engaged in research involving sensitive applications, the analyzer requires a very high level of accuracy.

2. Integration with Other AHV Servers

It may also regain its significance if you choose large-scale oligo synthesis, and therefore, scalability is important. Analyzers employed in the large-scale production mode must be capable of analyzing a large volume of data. They should be able to process sequences of this nature while handling one or many sequences at a time without having to reduce precision.

A large number of oligonucleotide manufacturing companies use industrial analysis equipment to control large scale production. They are designed to fit within production processes to produce quicker turnaround times. If the labs transforming from research-scale to the commercial production, it will be reasonable to invest in a scalable analyzer.

3. Manufacturing Workflows Integration

Thus, analyzers in a setting such as an oligo factory or an RNA synthesis company have to fit easily into the preexisting environment. This also encompasses compatibility with oligonucleotide manufacturing processes and other equipment. Integration guarantees that information processing is seamless and errors and delays are eliminated.

For example, many of the analyzers used in PPQ manufacturing have one or more built-in compliance parameters. To meet these requirements, the production processes meet appropriate regulatory provisions to guarantee that each batch manufactured complies with quality. Such tools are therefore important to ensure that the company provides the right consistency and meets the industry standards.

4. Ease of Use Interfaces for Researchers

It is essential to note that not all research settings have the luxury of technical support personnel. An oligo analyzer becomes an extremely valuable addition to a lab or a team, especially if a laboratory has a relatively small staff or a focused work team. Authors can study more instead of struggling with complicated tools — that is the benefit of having an understandable interface, logical reports’ output, and clear settings.

Lastly, the capabilities of many of the modern analyzers are also built-in with cloud integration and works remotely. These features are beneficial for multi-division projects or when interacting with an external partner such as an oligo CDMO. That is why two features are critical — availability and simplicity of using the tool for various tasks that do not require intensive research.

Conclusion

At Veliterbio we are aware of the significance of selecting instruments appropriate for your investigations. No matter you are in DNA oligo synthesis or in oligonucleotide drug discovery and development, the right Oligo Analyzer is essential to get the right answers.

Experience in oligo manufacturing, coupled with state-of-the-art technology, helps you stay current with your research endeavors. Let Veliterbio be your guide to selecting the right options for your requirements. Find out about our services now and improve your research experience.